Scanning Electron Microscopy (SEM) uses a high-energy electron beam to scan the surface of a sample. The interaction between the electron beam and the sample generates signals such as secondary electrons, backscattered electrons, and X-rays. These signals are collected by detectors and converted into images, revealing the surface morphology of the sample.

Transmission Electron Microscopy (TEM) is a technique in which a high-energy electron beam is transmitted through an electron-transparent sample (~100 nm thick). The interaction of electrons with the sample produces scattered and transmitted electrons, forming high-resolution two-dimensional images. Unlike SEM, Scanning Transmission Electron Microscopy (STEM) focuses the electron beam into a narrow point and scans the sample in a raster pattern. By using TEM or STEM, high-quality images with atomic-level resolution can be obtained. These images are widely used in cancer research, virology, materials science, and other fundamental studies.

KMD Bioscience offers comprehensive SEM and TEM services covering the entire workflow, from sample production to image analysis. Our professional team has extensive experience and advanced technical expertise to ensure the accuracy and reliability of results. We provide customized solutions tailored to meet diverse customer requirements. SEM enables observation of micro-surface morphology, such as cellular structures and surface defects, while TEM provides detailed insights into internal structures, such as lattice arrangements and nanoparticles.

TEM and STEM offer superior spatial resolution compared to SEM. However, compared to conventional analytical tools, these methods require more complex sample production and longer processing time. To obtain high-resolution structural and functional information, all samples should be preserved in their original state with a thickness of approximately 100 nm. We provide high-quality and relatively cost-effective routine TEM and STEM sample production services. Our offerings help researchers and their teams achieve specific research objectives.