The Aptamer In Vitro Screening Service provided by KMD Bioscience enables rapid and accurate identification of high-affinity and highly specific aptamers for clients, offering a cost-effective solution for their research projects. We provide a one-stop in vitro aptamer screening solution by flexibly leveraging the natural evolution of ligand systems through the Systematic Evolution of Ligands by EXponential Enrichment (SELEX) Technology (e.g., SELEX can identify distinct cells or detect molecular-level differences between two cell types).
Aptamers are short, 20–80 nucleotide (nt) single-stranded DNA (ssDNA) or RNA sequences, or proteins. They bind target molecules with high affinity and specificity by folding into specific three-dimensional structures. RNA sequences constitute the majority of nucleic acid aptamers, as they can be synthesized in vitro via transcription. The presence of the 2'-OH group in RNA may offer more diverse secondary structures compared to ssDNA molecules.
Aptamers are single-stranded nucleic acids (DNA or RNA) capable of binding predetermined targets with high affinity and specificity. They can be defined as "artificial antibodies" and are widely applied in fundamental life science research, clinical diagnostics, drug development, etc. KMD Bioscience has assembled a team of highly skilled experts with extensive experience in Aptamer In Vitro Screening, providing clients with a high-quality service.
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