KMD Bioscience has long been dedicated to antibody development research, with an experienced technical team, mature and stable process systems, and comprehensive antibody production facilities. We offer recombinant monoclonal antibody (mAb) generation services from multiple species, including mouse, rabbit, alpaca, bovine, sheep, and chicken.
Compared with conventional mouse mAbs, rabbit‑derived mAbs exhibit significant advantages in binding affinity and antigen recognition. They are now widely used in basic life science research, in vitro diagnostic reagent development, and therapeutic antibody candidate screening. In terms of binding affinity, the dissociation constant (KD) of rabbit mAbs generally reaches the picomolar range, whereas most mouse mAbs display affinities in the nanomolar to sub‑nanomolar range—meaning that rabbit antibodies have roughly a hundred‑fold higher antigen‑binding affinity. Regarding epitope recognition, the rabbit immune system can precisely distinguish subtle epitope differences on antigen surfaces, inducing the production of highly specific antibodies against particular epitopes; simultaneously, its immune response covers a broader epitope repertoire, facilitating the isolation of diverse positive clones that recognize distinct antigenic determinants.
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