Interleukin receptors/binding proteins are membrane-bound or soluble proteins that can specifically recognize and bind interleukin ligands, mediating the effective transmission of interleukin signals into the cell. They include heterodimeric receptor complexes, common γ-chain receptors, and soluble binding proteins, and regulate signal intensity, duration, and cell specificity. Abnormal expression of these molecules is associated with various immune diseases and represents an important node for drug intervention.

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