Lyases

Lyases are enzymes that catalyze the non-hydrolytic cleavage or synthesis of substrates, capable of breaking carbon-carbon, carbon-oxygen, and carbon-nitrogen bonds without relying on hydrolysis or oxidation. They play key roles in critical pathways such as glycolysis, the tricarboxylic acid cycle, and amino acid metabolism, serving as important regulatory nodes for cellular energy metabolism and intermediate metabolite generation.