Extracellular Matrix

The extracellular matrix is a macromolecular composite network secreted by cells into the extracellular space, including collagens, elastin, fibronectin, and laminin. They not only provide structural support and elasticity for tissues but also establish bidirectional signal transmission with cells through receptors such as integrins, regulating cell adhesion, migration, proliferation, and differentiation, and playing a key role in tissue development and regeneration.