Apoptosis-related proteins are protein molecules involved in regulating programmed cell death, ensuring the precise clearance of aged, damaged, or redundant cells during development, immune homeostasis, and tissue renewal through exquisite intrinsic molecular mechanisms. These molecules dynamically respond to internal and external signals through protein-protein interactions, conformational changes, post-translational modifications, and other means, forming a precise life-death decision network. Their dysfunction is directly involved in the pathogenesis of tumors, autoimmune diseases, and neurodegenerative diseases, making them an important target group for disease intervention.

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