Autoimmune Targets

Autoimmune target proteins are a class of key molecules involved in the onset and progression of autoimmune diseases. They include pro-inflammatory cytokines such as TNF-α, IL-1β, IL-6, IL-17, IFN-γ, and other pro-inflammatory cytokines and their receptors, as well as autoantigens, complement components, and molecules associated with immune tolerance. By mediating the amplification of inflammatory signals, the activation of immune cells, and tissue damage, these proteins play a central role in diseases such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease. They serve as important tools for studying the mechanisms of autoimmune diseases and for developing therapeutic antibody drugs.