Felinized antibody

Felinized antibodies are cat or cat-engineered antibodies for feline medicine, generated by grafting anti-feline antigen murine variable regions onto a feline framework (felinization) or screening feline immune libraries, reducing anti-antibody responses in cats for diagnosing and treating feline infectious disease, inflammation, and tumors. With rising pet-cat populations and precision-medicine demand, felinized antibodies show broad promise in veterinary mAb drugs and feline diagnostic reagents. Recombinant felinized antibodies and feline IgG/Fc/variable-region proteins support feline diagnostics, pet mAb development, and feline immunogenicity assessment.