Rabbit Anti Human respiratory syncytial virus (RSV) Fusion Glycoprotein Antibody
-
Product Number
SMAG3238
-
Alias
Anti-F Antibody,Anti-HRSVgp08 Antibody
-
Specifications
- 50ul
- 100ul
Product Description
| Alias | Anti-F Antibody,Anti-HRSVgp08 Antibody |
| Catalog Number | SMAG3238 |
| Product Description | This antibody was obtained from a rabbit immunized with purified, recombinant Human RSV fusion glycoprotein |
| Host | Rabbit |
| Size | 50ul,100ul |
| Clonity | Monoclonal |
| Purification | 亲和纯化 |
| Formulation | 0.2 μm filtered solution in PBS. |
| Background | Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneumovirus of the family paramyxoviridae. Like other members of the family, HRSV has two major surface glycoproteins (G and F) that play important roles in the initial stages of the infectious cycle. The G protein mediates attachment of the virus to cell surface receptors, while the F protein promotes fusion of the viral and cellular membranes, allowing entry of the virus ribonucleoprotein into the cell cytoplasm. The fusion (F) protein of RSV is synthesized as a nonfusogenic precursor protein (F), which during its migration to the cell surface is activated by cleavage into the disulfide-linked F1 and F2 subunits. This fusion is pH independent and occurs directly at the outer cell membrane, and the F2 subunit was identifed as the major determinant of RSV host cell specificity. The trimer of F1-F2 interacts with glycoprotein G at the virion surface. Upon binding of G to heparan sulfate, the hydrophobic fusion peptide is unmasked and induces the fusion between host cell and virion membranes. Notably, RSV fusion protein is unique in that it is able to interact directly with heparan sulfate and therefore is sufficient for virus infection. Furthermore, the fusion protein is also able to trigger p53-dependent apoptosis. |
| Immunogen | Recombinant Human RSV Fusion Glycoprotein / RSV-F |
| Application | ELISA |
| Recommended Dilution | ELISA 1:1000-1:2000 |
| Tag | Unconjugated |
| Storage Condition | Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | 冰袋运输 |
- Protein Platform
- Protein Expression Services
- Protein Modification & Detection Services
- Protein Interaction Services
- Protein Purification Service
- Antibody Discovery Platform
- VHH Antibody Platform
- Phage Display Platform
- Antibody Humanization Platform
- Single B Cell Screening Platform
- Antibody Expression & Validation Platform
- Peptide Library Platform
- Custom Antibody Platform
- Innovative Drug Discovery Platform
- Product Center
- Proteins
- Antibodies
- Raw Materials Reagents
- Small Molecule Reagents
- Peptide Products
- Nanoparticle Products
- Contact Us
- Phone：400-621-6806
- Mobile：13110936064（WeC
- E-mail：[email protected]
- Address：Room 108, Building 10, No. 6 Hechang Road, Wuqing Development Zone, Tianjin City
-
WeChat
-
Service Account
-
400-621-6806 -
3599163699 -
Monday to Friday 9:00-18:00 -
-
0
-
