Influenza A H1N1 Hemagglutinin,ECD,His Tag
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Product Number
PA161
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Alias
HA，Hemagglutinin
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Specifications
- 100ug
Product Description
| Alias | HA，Hemagglutinin |
| Catalog Number | PA161 |
| Product Description | A DNA sequence encoding the extracellular domain of Influenza A H1N1 Hemagglutinin (Met 1-Gln 529) (Native, HA1+HA2, uncleaved) was expressed with a C-terminal polyhistidine tag. |
| Molecular Name | HA |
| Species | H1N1 |
| Host | HEK293 Cells |
| Size | 100ug |
| Purity | > 90 % as determined by SDS-PAGE. |
| Purification | 亲和纯化 |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Background | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| Tag | His |
| Virus Titer | 59 kDa |
| Storage Condition | Store it under sterile conditions at -80℃. |
| Shipping Condition | 冰袋运输 |
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