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Recombinant Human IL-17E Protein

Recombinant Human IL-17E Protein

Product Number

KRP680

Alias

Recombinant human IL-17F protein, TNFRSF10C; DCR1; LIT; TRAILR3

Specifications
  • 100ug
  • 500ug
  • 1mg
Product Description
AliasRecombinant human IL-17F protein, TNFRSF10C; DCR1; LIT; TRAILR3
Catalog NumberKRP680
Product IntroductionRecombinant human interleukin-17E (IL-25) is a cytokine involved in type 2 immune responses and allergic inflammation. It is commonly used in research on allergies and inflammation, in immune models of parasitic infections, and in the study of the mechanisms underlying diseases such as asthma.
Molecular NameIL25 
SpeciesHuman
HostE.coli
Size100ug,500ug,1mg
Purity >97%, determined by SDS-PAGE.
ConcentrationContact your sales manager to get the concentration of the latest batch.
PurificationAffinity Purification
Endotoxin<0.01 EU/μg, determined by LAL method.
BackgroundMembers of the IL-17 cytokine family are primarily produced by epithelial cells and other cell types. Their main function is to promote type 2 immune responses (Th2), and they play an important role in combating parasitic infections and in allergic diseases (such as asthma).
ApplicationWB, ELISA
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Predicted Molecular Weight17 kDa
Predicted N TerminusMet
ReconstitutionIt is recommended that the lyophilized human IL-17E protein be dissolved in 4 mM HCl at a concentration of 100 μg/ml for further dilution as the working concentration.
Storage ConditionSamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Stability Repeated freezing and thawing is not recommended.
Uniprot IDQ9H293
NoteFor Research Use Only
References1. Saadoun, D. et al. (2011) Curr. Pharm. Des. 17:3781. 2. Iwakura, Y. et al. (2011) Immunity 34:149. 3. Lee, J. et al. (2001) J. Biol. Chem. 276:1660. 4. Fort, M.M. et al. (2001) Immunity 15:985. 5. Zhao, A. et al. (2010) J. Immunol. 185:6921. 6. Suzukawa, M. et al. (2012) J. Immunol. 189:3641. 7. Corrigan, C.J. et al. (2011) Proc. Natl. Acad. Sci. USA 108:1579. 8. Petersen, B.C. et al. (2012) Nat. Med. 18:751. 9. Wang, Y.­H. et al. (2007) J. Exp. Med. 204:1837. 10. Rickel, E.A. et al. (2008) J. Immunol. 181:4299. 11. Hurst, S.D. et al. (2002) J. Immunol. 169:443. 12. Kleinschek, M.A. et al. (2007) J. Exp. Med. 204:161. 13. Cao, Q. et al. (2011) J. Am. Soc. Nephrol. 22:1229. 14. Stock, P. et al. (2009) J. Immunol. 182:5116. 15. Caruso, R. et al. (2009) Gastroenterology 136:2270. 16. Goswami, S. et al. (2009) Nat. Immunol. 10:496. 17. Sonobe, Y. et al. (2009) J. Biol. Chem. 284:31834
FunctionRecombinant human interleukin-17E (IL-25) is a cytokine involved in type 2 immune responses and allergic inflammation. It is commonly used in research on allergies and inflammation, in immune models of parasitic infections, and in the study of the mechanisms underlying diseases such as asthma.
Product DeclarationThis product is intended for research use only and must not be used directly on humans or administered by injection.
Temperature RangeStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.
Product Full NameRecombinant Human IL-17E Protein
TargetIL-17E

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