Recombinant Mouse TIM-3/Havcr2 Protein, His Tag

Name: Recombinant Mouse TIM-3/Havcr2 Protein, His Tag
Brand: KMD Bioscience
SKU: MOP2296

MOP2296

Tim3, TIM 3, Timd3, hepatitis A virus cellular receptor 2

DATASHEET MSDS

Product Description

Alias	Tim3, TIM 3, Timd3, hepatitis A virus cellular receptor 2
Catalog Number	MOP2296
Molecular Name	Havcr2
Species	Mouse
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specifically identifies Th1 cells in both mice and human. Recently, identification of Galectin-9 as a ligand for TIM-3 has established the TIM-3-Galectin-9 pathway as an important regulator of Th1 immunity and tolerance induction. Engagement of Tim-3 by its ligand galectin-9 negatively regulates IFNgamma secretion and influences the ability to induce T cell tolerance in both mice and man.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	18.92 kDa
Note	仅供科研使用

Login