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Recombinant Mouse Gitr/Tnfrsf18 Protein, Fc & His Tag

Recombinant Mouse Gitr/Tnfrsf18 Protein, Fc & His Tag

Product Number

MOP2168

Alias

AITR, Gitr, tumor necrosis factor receptor superfamily, member 18

Specifications
  • 50ug
  • 100ug
Product Description
AliasAITR, Gitr, tumor necrosis factor receptor superfamily, member 18
Catalog NumberMOP2168
Molecular NameTnfrsf18
SpeciesMouse
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundGITR (glucocorticoid-induced tumor necrosis factor receptor) also known as TNFRSF18, is a surface receptor molecule that has been shown to be involved in inhibiting the suppressive activity of T-regulatory cells and extending the survival of T-effector cells.1 GITR is involved in the regulation of T-cell receptor mediated cell death. Constitutive expression of a transfected GITR gene induces resistance to apoptosis induced by anti CD3 monoclonal antibodies. GITR ligand interferes with the suppressor activity of CD4(+) CD25(+) regulatory T-cells.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight39.52 kDa
Note仅供科研使用

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