Recombinant Human EGF Protein
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Product Number
KRP695
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Alias
Pro-epidermal growth factor, EGF
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Specifications
- 100ug
- 500ug
- 1mg
Product Description
| Alias | Pro-epidermal growth factor, EGF |
| Catalog Number | KRP695 |
| Product Introduction | Recombinant human epidermal growth factor is a core growth factor that promotes epithelial cell proliferation and migration. Mainly used for research on skin and epithelial tissue repair, exploration of cell proliferation signaling pathways, and evaluation of cosmetic efficacy. |
| Molecular Name | EGF |
| Species | Human |
| Host | E.coli |
| Size | 100ug,500ug,1mg |
| Purity | >97%, determined by SDS-PAGE. |
| Concentration | Contact the sales manager to obtain the concentration of the latest batch. |
| Purification | Affinity Purification |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Background | A typical member of the epidermal growth factor family that strongly promotes the proliferation, migration, and differentiation of various cells including epithelial cells and fibroblasts by binding to EGFR receptors, playing a critical role in wound healing and tumor development. |
| Application | WB, ELISA |
| Predicted Molecular Weight | 12.7 kDa |
| Reconstitution | It is recommended that the lyophilized human EGF protein be dissolved in PBS at a concentration of 200 μg/ml for further dilution as the working concentration. Shipping Condition: Transport at ambient temperature. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -99℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | 6 kDa, d |
| Uniprot ID | P01133 |
| References | 1. Harris, R.C. et al. (2003) Exp. Cell Res. 284:2. 2. Carpenter, G. and Cohen, S. (1990) J. Biol. Chem. 265:7709. 3. Bell, G.I. et al. (1986) Nucl. Acids Res. 14:8427. 4. Carpenter, G. and Zendegui, J.G. (1986) Exp. Cell Res. 164:1. 5. Jorissen, R.N. et al. (2003) Exp. Cell Res. 284:31. 6. Gamett, D.C. et al. (1997) J. Biol. Chem. 272:12052. 7. Qian, X. et al. (1994) Proc. Natl. Acad. Sci. 91:1500. 8. Qian, X. et al. (1999) J. Biol. Chem. 274:574. |
| Function | Recombinant Human Epidermal Growth Factor is the core growth factor that promotes the proliferation and migration of epithelial cells. It is mainly used for research on skin and epithelial tissue repair, exploration of cell proliferation signaling pathways, and evaluation of cosmetic efficacy. |
| Product Declaration | This product is for research use only and must not be used directly on the human body or for injection. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -39℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human EGF Protein |
| Target | EGF |
FAQ
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What is the core function of EGF?
It is an epidermal growth factor that can stimulate the proliferation and migration of various epithelial and mesenchymal cells.
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What is its status in stem cell and organoid culture?
It is a classic factor for maintaining proliferation of neural stem cells (used in combination with FGF2); it is also an essential component in the culture systems of various epithelial organoids such as intestine, liver, lung, etc., used to maintain the proliferation of stem/progenitor cells.
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