Recombinant Human IL1B Protein, His Tag
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Product Number
KRP689
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Alias
IL-1βprotein,Interleukin 1βprotein, IL-1protein, IL1F2protein, IL1-betaprotein, Catabolinprotein
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Specifications
- 100ug
- 500ug
- 1mg
KRP689
IL-1βprotein,Interleukin 1βprotein, IL-1protein, IL1F2protein, IL1-betaprotein, Catabolinprotein
| Alias | IL-1βprotein,Interleukin 1βprotein, IL-1protein, IL1F2protein, IL1-betaprotein, Catabolinprotein |
| Catalog Number | KRP689 |
| Product Introduction | Recombinant human interleukin-1 β is a key pro-inflammatory cytokine that mediates acute inflammatory response and fever. Widely used in inflammation pathway activation research, immune cell activation experiments, and autoimmune disease models. |
| Molecular Name | IL1B |
| Species | Human |
| Host | E.coli |
| Size | 100ug,500ug,1mg |
| Purity | >97%, determined by SDS-PAGE. |
| Concentration | Contact the sales manager to obtain the concentration of the latest batch. |
| Purification | Affinity Purification |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Background | An important pro-inflammatory cytokine produced by macrophages activated by mechanisms such as the NLRP3 inflammasome, playing a central role in fever, acute phase responses, initiation of inflammation, and various auto-inflammatory diseases. |
| Application | WB, ELISA |
| Predicted Molecular Weight | 17 kDa |
| Reconstitution | It is recommended that the lyophilized human I IL-1β protein be dissolved in PBS at a concentration of 100-200 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -94℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Uniprot ID | P01584 |
| References | 1. Allan, S.M. et al. (2005) Nat. Rev. Immunol. 5:629. 2. Boraschi, D. and A. Tagliabue (2006) Vitam. Horm. 74:229. 3. Kornman, K.S. (2006) Am. J. Clin. Nutr. 83:475S. 4. Isoda, K. and F. Ohsuzu (2006) J. Atheroscler. Thromb. 13:21. 5. March, C.J. et al. (1985) Nature 315:641. 6. Auron, P.E. et al. (1984) Proc. Natl. Acad. Sci. 81:7907. 7. Martinon, F. and J. Tschopp (2007) Cell Death Differ. 14:10. |
| Function | Recombinant human interleukin-1β is a key pro-inflammatory cytokine that mediates acute inflammatory responses and fever. It is widely used in inflammation pathway activation research, immune cell activation experiments, and autoimmune disease models. |
| Product Declaration | This product is for research use only and must not be used directly on the human body or for injection. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -34℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human IL-1β Protein |
| Target | IL-1β |
It is a potent pro-inflammatory cytokine that plays a central role in fever, inflammation initiation, and immune cell activation.
It is mainly used to simulate inflammatory damage environments. For example, to study its effects on the function (or aging) of mesenchymal stem cells, or to construct in vitro inflammatory models for diseases such as osteoarthritis.
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