Recombinant Human IL2 Protein, His Tag

Product Number

KRP686

Alias

Interleukin-2, IL-2, T-cell growth factor, TCGF

Specifications

100ug
500ug
1mg

DATASHEET MSDS

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Product Description

Alias	Interleukin-2, IL-2, T-cell growth factor, TCGF
Catalog Number	KRP686
Product Introduction	Recombinant human interleukin-2 is a key cytokine for T cell proliferation and activation. Mainly used for T cell expansion in vitro, immunotherapy research, and cancer immunology experiments.
Molecular Name	IL2
Species	Human
Host	E.coli
Size	100ug,500ug,1mg
Purity	>97%, determined by SDS-PAGE.
Concentration	Contact the sales manager to obtain the concentration of the latest batch.
Purification	Affinity Purification
Endotoxin	<0.01 EU/μg, determined by LAL method.
Background	Mainly produced by activated T cells, a key factor for the growth, proliferation, and differentiation of T cells, historically known as 'T cell growth factor', an important target in cancer immunotherapy and immunosuppression research.
Application	WB, ELISA
Predicted Molecular Weight	15.5 kDa
Reconstitution	It is recommended that the lyophilized human IL-2 protein be dissolved in 100 mM acetic acid at a concentration of 100-200 μg/ml for further dilution as the working concentration.
Storage Condition	Samples are stable for up to twelve months from date of receipt at -20℃ to -90℃. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Stability	Repeated freezing and thawing is not recommended.
Molecular Weight	13 kDa
Uniprot ID	P60568
References	1. Ma, A. et al. (2006) Annu. Rev. Immunol. 24:657. 2. Gaffen, S.L. and K.D. Liu (2004) Cytokine 28:109. 3. Taniguchi, T. et al. (1983) Nature 302:305. 4. Mosmann, T.R. et al. (1987) J. Immunol. 138:1813. 5. Liparoto, S.F. et al. (2002) Biochemistry 41:2543. 6. Wang, X. et al. (2005) Science 310:1159. 7. Bodnar, A. et al. (2008) Immunol. Lett. 116:117. 8. Jaleco, S. et al. (2003) J. Immunol. 171:61. 9. Malek, T.R. (2003) J. Leukoc. Biol. 74:961. 10. Laurence, A. et al. (2007) Immunity 26:371. 11. Kryczek, I. et al. (2007) J. Immunol. 178:6730. 12. Afzali, B. et al. (2007) Clin. Exp. Immunol. 148:32. 13. Fehervari, Z. et al. (2006) Trends Immunol. 27:109
Function	Recombinant human interleukin-2 is a key cytokine for T cell proliferation and activation. It is mainly used for in vitro T cell expansion, immune therapy research, and cancer immunology experiments.
Product Declaration	This product is for research use only and must not be used directly on the human body or for injection.
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -30℃. Avoid repeated freeze-thaw cycles.
Product Full Name	Recombinant Human IL-2 Protein
Target	IL-2

FAQ

Why is IL-2 called the 'T cell growth factor'?

Because it specifically promotes the proliferation, activation, and differentiation of T lymphocytes, being a key regulator of adaptive immune responses.
What role does it play in modern cell therapy?

It is the core culture component for the ex vivo large-scale expansion and activation of cytotoxic T cells, CAR-T cells, and NK cells for adoptive immunotherapy.

PRODUCT CENTER

Recombinant Human IL2 Protein, His Tag

Product Number

Alias

Specifications

Why is IL-2 called the 'T cell growth factor'?

What role does it play in modern cell therapy?

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