Recombinant Human M-CSF Protein

Product Number

KRP684

Alias

Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF

Specifications

100ug
500ug
1mg

DATASHEET MSDS

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Product Description

Alias	Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF
Catalog Number	KRP684
Product Introduction	Recombinant human macrophage colony-stimulating factor is an essential factor for the development and activation of monocyte/macrophage lineages. Commonly used for in vitro differentiation of macrophages, immune regulation research, and construction of tumor associated macrophage models.
Molecular Name	CSF1
Species	Human
Host	E.coli
Size	100ug,500ug,1mg
Purity	>97%, determined by SDS-PAGE.
Concentration	Contact the sales manager to obtain the concentration of the latest batch.
Purification	Affinity Purification
Endotoxin	<0.01 EU/μg, determined by LAL method.
Background	A colony-stimulating factor that is a key regulator of the development, differentiation, survival, and functional activation of the monocyte/macrophage lineage, also involved in osteoclastogenesis and pregnancy regulation.
Application	WB, ELISA
Predicted Molecular Weight	18.5 kDa
Reconstitution	It is recommended that the lyophilized human M-CSF protein be dissolved in PBS at a concentration of 50-500 μg/mL for further dilution as the working concentration.
Storage Condition	Samples are stable for up to twelve months from date of receipt at -20℃ to -88℃. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Stability	Repeated freezing and thawing is not recommended.
Molecular Weight	37 kDa
Uniprot ID	P09603
References	2. Chitu, V. and E.R. Stanley (2006) Curr. Opin. Immunol. 18:39. 3. Fixe, P. and V. Praloran (1997) Eur. Cytokine Netw. 8:125. 4. Ryan, G.R. et al. (2001) Blood 98:74. 5. Makrigiannakis, A. et al. (2006) Trends Endocrinol. Metab. 17:178. 6. Nandi, S. et al. (2006) Blood 107:786. 7. Rettenmier, C.W. and M.F. Roussel (1988) Mol. Cell Biol. 8:5026. 8. Suzu, S. et al. (1992) J. Biol. Chem. 267:16812. 9. Manos, M.M. (1988) Mol. Cell. Biol. 8:5035. 10. Koths, K. (1997) Mol. Reprod. Dev. 46:31. 11. Jang, MH. et al. (2006) J. Immunol. 177:4055. 12. Kawasaki, E.S. et al. (1985) Science 230: 291. 13. Wong, G.G. et al. (1987) Science 235:1504.
Function	Recombinant Human Macrophage Colony-Stimulating Factor is an essential factor for the development and activation of the monocyte/macrophage lineage. It is commonly used for in vitro differentiation of macrophages, immune regulation research, and construction of tumor-associated macrophage models.
Product Declaration	This product is for research use only and must not be used directly on the human body or for injection.
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -28℃. Avoid repeated freeze-thaw cycles.
Product Full Name	Recombinant Human M-CSF Protein
Target	M-SCF

FAQ

What are the functions of M-CSF?

Macrophage colony-stimulating factor, specifically stimulates the production, differentiation, and functional activation of the monocyte/macrophage lineage.
How is it used in stem cell differentiation?

It is a core factor driving the differentiation of hematopoietic stem cells or iPSCs into the monocyte/macrophage lineage, and can be used in combination with IL-4, GM-CSF, etc. to obtain macrophages with different functional subtypes.

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Recombinant Human M-CSF Protein

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