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Recombinant Human IL-17E Protein

Recombinant Human IL-17E Protein

Product Number

KRP680

Alias

TNFRSF10C, DCR1, LIT, TRAILR3

Specifications
  • 100ug
  • 500ug
  • 1mg
Product Description
AliasTNFRSF10C, DCR1, LIT, TRAILR3
Catalog NumberKRP680
Product IntroductionRecombinant human interleukin-17E (IL-25) is a cytokine involved in type 2 immune response and allergic inflammation. Commonly used in allergy and inflammation research, parasitic infection immune models, and exploration of the mechanisms of related diseases such as asthma.
Molecular NameIL25
SpeciesHuman
HostE.coli
Size100ug,500ug,1mg
Purity>97%, determined by SDS-PAGE.
ConcentrationContact the sales manager to obtain the concentration of the latest batch.
PurificationAffinity Purification
Endotoxin<0.01 EU/μg, determined by LAL method.
BackgroundA member of the IL-17 cytokine family, mainly produced by epithelial cells, primarily functions to promote type 2 immune responses,playing a significant role in anti-parasitic infections and allergic diseases such as asthma.
ApplicationWB, ELISA
Predicted Molecular Weight17 kDa
ReconstitutionIt is recommended that the lyophilized human IL-17E protein be dissolved in 4 mM HCl at a concentration of 100 μg/ml for further dilution as the working concentration.
Storage ConditionSamples are stable for up to twelve months from date of receipt at -20℃ to -85℃. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
StabilityRepeated freezing and thawing is not recommended.
Uniprot IDQ9H293
References1. Saadoun, D. et al. (2011) Curr. Pharm. Des. 17:3781. 2. Iwakura, Y. et al. (2011) Immunity 34:149. 3. Lee, J. et al. (2001) J. Biol. Chem. 276:1660. 4. Fort, M.M. et al. (2001) Immunity 15:985. 5. Zhao, A. et al. (2010) J. Immunol. 185:6921. 6. Suzukawa, M. et al. (2012) J. Immunol. 189:3641. 7. Corrigan, C.J. et al. (2011) Proc. Natl. Acad. Sci. USA 108:1579. 8. Petersen, B.C. et al. (2012) Nat. Med. 18:751. 9. Wang, Y.­H. et al. (2007) J. Exp. Med. 204:1837. 10. Rickel, E.A. et al. (2008) J. Immunol. 181:4299. 11. Hurst, S.D. et al. (2002) J. Immunol. 169:443. 12. Kleinschek, M.A. et al. (2007) J. Exp. Med. 204:161. 13. Cao, Q. et al. (2011) J. Am. Soc. Nephrol. 22:1229. 14. Stock, P. et al. (2009) J. Immunol. 182:5116. 15. Caruso, R. et al. (2009) Gastroenterology 136:2270. 16. Goswami, S. et al. (2009) Nat. Immunol. 10:496. 17. Sonobe, Y. et al. (2009) J. Biol. Chem. 284:31834
FunctionRecombinant Human Interleukin-17E (IL-25) is a cytokine involved in Type 2 immune responses and allergic inflammation. It is commonly used in research on allergies and inflammation, immune models for parasitic infections, and exploration of the mechanisms of diseases such as asthma.
Product DeclarationThis product is for research use only and must not be used directly on the human body or for injection.
Temperature RangeStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.
Product Full NameRecombinant Human IL-17E Protein
TargetIL-17E
FAQ
  • What are the main functions of IL-17E?

    It belongs to the IL-17 cytokine family and mainly participates in type 2 immune responses, related to allergic diseases and anti-parasitic immunity.

  • Is it commonly used in stem cell research?

    It is not commonly used as a core growth factor. It is mainly used to study the effects of specific immune microenvironments (Th2-type inflammation) on the function of epithelial stem cells or mesenchymal stem cells.

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