Recombinant Human IL-17E Protein
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Product Number
KRP680
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Alias
TNFRSF10C, DCR1, LIT, TRAILR3
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Specifications
- 100ug
- 500ug
- 1mg
KRP680
TNFRSF10C, DCR1, LIT, TRAILR3
| Alias | TNFRSF10C, DCR1, LIT, TRAILR3 |
| Catalog Number | KRP680 |
| Product Introduction | Recombinant human interleukin-17E (IL-25) is a cytokine involved in type 2 immune response and allergic inflammation. Commonly used in allergy and inflammation research, parasitic infection immune models, and exploration of the mechanisms of related diseases such as asthma. |
| Molecular Name | IL25 |
| Species | Human |
| Host | E.coli |
| Size | 100ug,500ug,1mg |
| Purity | >97%, determined by SDS-PAGE. |
| Concentration | Contact the sales manager to obtain the concentration of the latest batch. |
| Purification | Affinity Purification |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Background | A member of the IL-17 cytokine family, mainly produced by epithelial cells, primarily functions to promote type 2 immune responses,playing a significant role in anti-parasitic infections and allergic diseases such as asthma. |
| Application | WB, ELISA |
| Predicted Molecular Weight | 17 kDa |
| Reconstitution | It is recommended that the lyophilized human IL-17E protein be dissolved in 4 mM HCl at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -85℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Uniprot ID | Q9H293 |
| References | 1. Saadoun, D. et al. (2011) Curr. Pharm. Des. 17:3781. 2. Iwakura, Y. et al. (2011) Immunity 34:149. 3. Lee, J. et al. (2001) J. Biol. Chem. 276:1660. 4. Fort, M.M. et al. (2001) Immunity 15:985. 5. Zhao, A. et al. (2010) J. Immunol. 185:6921. 6. Suzukawa, M. et al. (2012) J. Immunol. 189:3641. 7. Corrigan, C.J. et al. (2011) Proc. Natl. Acad. Sci. USA 108:1579. 8. Petersen, B.C. et al. (2012) Nat. Med. 18:751. 9. Wang, Y.H. et al. (2007) J. Exp. Med. 204:1837. 10. Rickel, E.A. et al. (2008) J. Immunol. 181:4299. 11. Hurst, S.D. et al. (2002) J. Immunol. 169:443. 12. Kleinschek, M.A. et al. (2007) J. Exp. Med. 204:161. 13. Cao, Q. et al. (2011) J. Am. Soc. Nephrol. 22:1229. 14. Stock, P. et al. (2009) J. Immunol. 182:5116. 15. Caruso, R. et al. (2009) Gastroenterology 136:2270. 16. Goswami, S. et al. (2009) Nat. Immunol. 10:496. 17. Sonobe, Y. et al. (2009) J. Biol. Chem. 284:31834 |
| Function | Recombinant Human Interleukin-17E (IL-25) is a cytokine involved in Type 2 immune responses and allergic inflammation. It is commonly used in research on allergies and inflammation, immune models for parasitic infections, and exploration of the mechanisms of diseases such as asthma. |
| Product Declaration | This product is for research use only and must not be used directly on the human body or for injection. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human IL-17E Protein |
| Target | IL-17E |
It belongs to the IL-17 cytokine family and mainly participates in type 2 immune responses, related to allergic diseases and anti-parasitic immunity.
It is not commonly used as a core growth factor. It is mainly used to study the effects of specific immune microenvironments (Th2-type inflammation) on the function of epithelial stem cells or mesenchymal stem cells.
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