Recombinant Human IL7 Protein, His Tag

Product Number

KRP678

Alias

Recombinant Human Interleukin-7, IL7, IL-7

Specifications

100ug
500ug
1mg

DATASHEET MSDS

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Product Description

Alias	Recombinant Human Interleukin-7, IL7, IL-7
Catalog Number	KRP678
Product Introduction	Recombinant human interleukin-7 is an essential cytokine for lymphocyte development, survival, and homeostasis maintenance. Mainly used for immunological research, in vitro expansion of T cells and B cells, and construction of immune deficiency related disease models.
Molecular Name	IL7
Species	Human
Host	E.coli
Size	100ug,500ug,1mg
Purity	>97%, determined by SDS-PAGE.
Concentration	Contact the sales manager to obtain the concentration of the latest batch.
Purification	Affinity Purification
Endotoxin	<0.01 EU/μg, determined by LAL method.
Background	A cytokine essential for the development and homeostasis of lymphocytes, which promotes the survival, proliferation, and differentiation of B cells and T cells, especially naïve and memory T cells.
Application	WB, ELISA
Predicted Molecular Weight	17 kDa
Reconstitution	It is recommended that the lyophilized human IL-7 protein be dissolved in PBS at a concentration of 100 μg/ml for further dilution as the working concentration.
Storage Condition	Samples are stable for up to twelve months from date of receipt at -20℃ to -83℃. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Stability	Repeated freezing and thawing is not recommended.
Uniprot ID	P13232
References	1. Sasson, S.C. et al. (2006) Curr. Drug Targets 7:1571. 2. Barata, J.T. et al. (2006) Exp. Hematol. 34:1133. 3. Goodwin, R.G. et al. (1990) Proc. Natl. Acad. Sci. USA 86:302. 4. Namen, A.E. et al. (1988) Nature 333:571. 5. Shalapour, S. et al. (2012) PLoS ONE 7: e31939. 6. Saini, M. et al. (2009) Blood 113:5793. 7. Park, J.H. et al. (2004) Immunity 21:289. 8. Vranjkovic, A. et al. (2007) Int. Immunol. 19:1329. 9. Sudo, T. et al. (1993) Proc. Natl. Acad. Sci. 90:9125. 10. Seddon, B. et al. (2003) Nat. Immunol. 4:680. 11. Schluns, K.S. et al. (2000) Nat. Immunol. 5:426. 12. Peschon, J.J. et al. (1994) J. Exp. Med. 180:1955. 13. Pribyl, J.A. and T.W. LeBien (1996) Proc. Natl. Acad. Sci. 93:10348. 14. Johnson, K. et al. (2012) J. Immunol. 188:6084. 15. Nodland, S.E. et al. (2011) Blood 118:2116.
Function	Recombinant human interleukin-7 is a cytokine that is essential for lymphocyte development, survival, and homeostasis maintenance. It is primarily used for immunology research, in vitro expansion of T cells and B cells, and the construction of immune deficiency disease models.
Product Declaration	This product is for research use only and must not be used directly on the human body or for injection.
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -23℃. Avoid repeated freeze-thaw cycles.
Product Full Name	Recombinant Human IL-7 Protein
Target	IL-7

FAQ

What is the main biological function of IL-7?

It is a key factor in lymphocyte development, especially crucial for the survival, proliferation, and differentiation of T cells and B cells.
How is it applied in stem cell culture or differentiation?

It is mainly applied in the directed differentiation of hematopoietic stem cells into the T lymphocyte lineage, and it is also one of the key culture factors for the in vitro expansion of CAR-T and other immunotherapy T cells.

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Recombinant Human IL7 Protein, His Tag

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Specifications

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