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Recombinant Human Noggin Protein, C-His Tag

Recombinant Human Noggin Protein, C-His Tag

Product Number

KRP407

Alias

Noggin,NOG,SYM1,SYNS1,SYNS1A

Specifications
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
Product Description
AliasNoggin,NOG,SYM1,SYNS1,SYNS1A
Catalog NumberKRP407
Expression SystemHEK293F Cells
Product DescriptionHuman NOG(28-232 aa)
Molecular NameNOG
SpeciesHuman
Size20ug, 50ug, 100ug, 200ug, 1mg
Purity≥95%
ConcentrationContact the sales manager to obtain the concentration of the latest batch.
PurificationAffinity Purification
Endotoxin< 0.1 EU per ug
FormulationSupplied in PBS
BackgroundInhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (PubMed:21976273, PubMed:26643732). {ECO:0000269|PubMed:12478285, ECO:0000269|PubMed:21976273, ECO:0000269|PubMed:26643732}.
Biological ActivityImmobilized Human BMP2 at 1 μg/mL (100 μL/well) can bind Noggin with a linearrange of 2- 57 ng/mL.
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight35-38 kDa
Uniprot IDQ13253
Product DeclarationThis product is for research use only and must not be used directly on the human body or for injection.

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