KRP195
bFGF,FGF basic,FGF2,FGF-2,HBGF-2,Prostatropin,Fibroblast growth factor 2,Basic fibroblast growth factor,Heparin-binding growth factor 2,Fibroblast growth factor 2,Basic fibroblast growth factor
| Alias | bFGF,FGF basic,FGF2,FGF-2,HBGF-2,Prostatropin,Fibroblast growth factor 2,Basic fibroblast growth factor,Heparin-binding growth factor 2,Fibroblast growth factor 2,Basic fibroblast growth factor |
| Catalog Number | KRP195 |
| Product Introduction | Fgf2 is a heparin-binding secreted protein that participates in tissue repair and embryonic development by promoting the proliferation and migration of various cell types. |
| Expression System | E. coli |
| Product Description | Mouse Fgf2(Ala11-Ser154) |
| Molecular Name | Fgf2 |
| Species | Mouse |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Purity | ≥95% |
| Concentration | Contact the sales manager to obtain the concentration of the latest batch. |
| Purification | Affinity Purification |
| Endotoxin | ＜1.0EU/ug |
| Formulation | Supplied in PBS |
| Background | Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Also acts as an integrin ligand which is required for FGF2 signaling (By similarity). Binds to integrin ITGAV:ITGB3 (By similarity). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity). Functions as a potent mitogen in vitro (By similarity). Can induce angiogenesis (By similarity). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity). {ECO:0000250|UniProtKB:P09038}. |
| Biological Activity | Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 0.3-1.8 ng/mL. |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 22 kDa |
| Uniprot ID | P15655 |
| Product Declaration | This product is for research use only and must not be used directly on the human body or for injection. |
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