Human IL18 Protein
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Product Number
KMPH1232
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Alias
Interleukin-18, IL18, interleukin 18, IGIF, IL-18, IL-1g, IL1F4
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Specifications
- 10ug
- 100ug
- 500ug
- 1mg
Product Description
| Alias | Interleukin-18, IL18, interleukin 18, IGIF, IL-18, IL-1g, IL1F4 |
| Catalog Number | KMPH1232 |
| Molecular Name | Interleukin 18 IL 18 |
| Species | Human |
| Host | E.coli |
| Size | 10ug, 100ug, 500ug, 1mg |
| Purity | > 95% as determined by Tris-Bis PAGE, > 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Formulation | Lyophilized from 0.22um filtered solution in 20mM PB, 250mM NaCl, 50mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Background | Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. |
| Application | SDS-PAGE, WB, ELISA |
| Tag | No Tag |
| Biological Activity | Immobilized Human IL-18 at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-18BP, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). |
| Predicted N Terminus | Tyr 37 |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
| Sequence | YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISM YKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFF QRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTV QNED |
| Molecular Weight | The protein has a predicted MW of 18.2 kDa same as Tris-Bis PAGE result. |
| Uniprot ID | Q14116-1 |
| Note | For Research Use Only! |
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