Rat PRSS8 Protein, His Tag
-
Product Number
KMP4268
-
Alias
丝氨酸蛋白酶8, PRSS8 Protein, Rat PRSS8 Protein, His Tag
-
Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 丝氨酸蛋白酶8, PRSS8 Protein, Rat PRSS8 Protein, His Tag |
| Catalog Number | KMP4268 |
| Product Description | The Rat PRSS8 Protein(KMP4268) is produced in HEK293 Cells. A DNA sequence encoding the rat Prss8 (NP_620191.1) (Met1-Arg322) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | PRSS8 |
| Species | Rat |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from human seminal fluid and is highly expressed in prostate, lung, kidney, salivary gland and pancreas. Prostasin is expressed as a glycosyl-phosphatidylinositol (GPI)-anchored membrane protein in prostate epithelial cells, and also exists as a secreted proteolytic enzyme possibly via tryptic cleavage of its COOH-terminal hydrophobic domain. Prostasin is found to activate the epithelial sodium channel (ENaC) which is tightly regulated and is critical for maintaining salt and fluid balance in the lung and kidney in both normal and pathological conditions. Accordingly, prostasin has been proposed as a target for therapeutic inhibition in cystic fibrosis. Besides, prostasin inhibits prostate and breast cancer cell invasion in vitro, suggesting a functional role as a suppressor of tumor invasion, as well as a regulator of gene expression during inflammation. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 32.9 kDa |
- Protein Platform
- Protein Expression Services
- Protein Modification & Detection Services
- Protein Interaction Services
- Protein Purification Service
- Antibody Discovery Platform
- VHH Antibody Platform
- Phage Display Platform
- Antibody Humanization Platform
- Single B Cell Screening Platform
- Antibody Expression & Validation Platform
- Peptide Library Platform
- Custom Antibody Platform
- Innovative Drug Discovery Platform
- Product Center
- Proteins
- Antibodies
- Raw Materials Reagents
- Small Molecule Reagents
- Peptide Products
- Nanoparticle Products
- Contact Us
- Phone：400-621-6806
- Mobile：13110936064（WeC
- E-mail：[email protected]
- Address：Room 108, Building 10, No. 6 Hechang Road, Wuqing Development Zone, Tianjin City
-
WeChat
-
Service Account
-
400-621-6806 -
3599163699 -
Monday to Friday 9:00-18:00 -
-
0
-
