Rat P-Selectin Protein, hFc Tag
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Product Number
KMP4237
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Alias
P-选择素, P-Selectin Protein, Rat P-Selectin Protein, hFc Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | P-选择素, P-Selectin Protein, Rat P-Selectin Protein, hFc Tag |
| Catalog Number | KMP4237 |
| Product Description | The Rat P-Selectin Protein(KMP4237) is produced in HEK293 Cells. A DNA sequence encoding the rat Selp (AAI01920.1) (Met1-Gln700) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | P-Selectin |
| Species | Rat |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | P selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. SELP mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P selectin is a cell adhesion molecule on the surface of activated endothelial cells. Cellular adhesion molecules are a large family of proteins that attach the cytoskeleton and intracellular signaling cascades with the extracellular environment. SELP is a calcium-dependent receptor for myeloid cells that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 98.7 kDa |
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