Rabbit IL17 Protein, His Tag
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Product Number
KMP4171
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Alias
白细胞介素-17, IL17 Protein, Rabbit IL17 Protein, His Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白细胞介素-17, IL17 Protein, Rabbit IL17 Protein, His Tag |
| Catalog Number | KMP4171 |
| Product Description | The Rabbit IL17 Protein(KMP4171) is produced in Insect Cells. A DNA sequence encoding the rabbit IL17A (XP_002714544.1) (Gly24-Ala153) is expressed with a polyhistidine tag at the N-terminus. |
| Molecular Name | IL17 |
| Species | Rabbit |
| Host | Insect Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 20mM PBS, 500mM NaCl, 10% Glycerol, pH7.0 |
| Background | IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 17.3 kDa |
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