Mouse TNFRSF13C Protein, rFc Tag
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Product Number
KMP3895
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Alias
TNF受体超家族成员13C, TNFRSF13C Protein, Mouse TNFRSF13C Protein, rFc Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | TNF受体超家族成员13C, TNFRSF13C Protein, Mouse TNFRSF13C Protein, rFc Tag |
| Catalog Number | KMP3895 |
| Product Description | The Mouse TNFRSF13C Protein(KMP3895) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Tnfrsf13c (NP_082351.1) (Met1-Ala71) is expressed with the Fc region of rabbit IgG at the C-terminus. |
| Molecular Name | TNFRSF13C |
| Species | Mouse |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 33.8 kDa |
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