Mouse PCSK9 Protein, mFc Tag
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Product Number
KMP3875
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Alias
前蛋白转化酶枯草溶菌素9, PCSK9 Protein, Mouse PCSK9 Protein, mFc Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 前蛋白转化酶枯草溶菌素9, PCSK9 Protein, Mouse PCSK9 Protein, mFc Tag |
| Catalog Number | KMP3875 |
| Product Description | The Mouse PCSK9 Protein(KMP3875) is produced in HEK293 Cells. A DNA sequence encoding the Mouse PCSK9 (NP_705793.1) (Met1-Gln694) is expressed with the Fc region of Mouse IgG1 at the C-terminus. |
| Molecular Name | PCSK9 |
| Species | Mouse |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 97.6 kDa |
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