Cynomolgus CEACAM6 Protein, His Tag
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Product Number
KMP3728
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Alias
癌胚抗原相关细胞粘附分子6, CEACAM6 Protein, Cynomolgus CEACAM6 Protein, His Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 癌胚抗原相关细胞粘附分子6, CEACAM6 Protein, Cynomolgus CEACAM6 Protein, His Tag |
| Catalog Number | KMP3728 |
| Product Description | The Cynomolgus CEACAM6 Protein(KMP3728) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus CEACAM6 (XP_005589488.1) (Met1-Pro323) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | CEACAM6 |
| Species | Cynomolgus |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 33.3 kDa |
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