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Human IL-12 Protein, His Tag

Human IL-12 Protein, His Tag

Product Number

KMP3536

Alias

白细胞介素, Human IL-12 Protein, His Tag, IL-12

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
Alias白细胞介素, Human IL-12 Protein, His Tag, IL-12
Catalog NumberKMP3536
Product DescriptionThe Human IL-12 Protein(KMP3536) is produced in HEK293 Cells. The target gene encoding the p35 subunit of human IL-12, termed as IL12A (P29459.2) (Met1-Ser219) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1 ; The target gene encoding the p40 subunit of human IL-12, termed as IL12B (NP_002178.2) (Met1-Ser328) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the heterodimer is purified. The purified protein is biotinylated in vitro.
Molecular NameIL-12
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundIL12A (Interleukin 12A) is a Protein Coding gene. Diseases associated with IL12A include Behcet Syndrome and Primary Biliary Cholangitis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and growth factor activity. IL12B (Interleukin 12B) is a Protein Coding gene. Diseases associated with IL12B include Immunodeficiency 29 and Takayasu Arteritis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein heterodimerization activity.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight60.13 kDa

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