Human RGMB Protein, His Tag

Name: Human RGMB Protein, His Tag
Brand: KMD Bioscience
SKU: KMP3411

KMP3411

排斥性引导分子 BMP 辅助受体 b, Human RGMB Protein, His Tag, RGMB

DATASHEET MSDS

Product Description

Alias	排斥性引导分子 BMP 辅助受体 b, Human RGMB Protein, His Tag, RGMB
Catalog Number	KMP3411
Product Description	The Human RGMB Protein(KMP3411) is produced in HEK293 Cells. The target gene encoding the human RGMB (NP_001012779.2) (Met1-Asn413) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	RGMB
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investigations demonstrated RGMB knockdown resulted in a reduced expression and activity of Caspase-3, accompanied with better survival in RGMB knockdown cells under serum starvation, which might be induced by its repression on MAPK JNK pathway. That RGMB may act as a negative regulator in breast cancer through BMP signaling.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	42 kDa

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