Human FGF8 Protein

Name: Human FGF8 Protein
Brand: KMD Bioscience
SKU: KMP3354

KMP3354

成纤维细胞生长因子 8, Human FGF8 Protein, FGF8

DATASHEET MSDS

Product Description

Alias	成纤维细胞生长因子 8, Human FGF8 Protein, FGF8
Catalog Number	KMP3354
Product Description	The Human FGF8 Protein(KMP3354) is produced in E. coli. The target gene encoding the human FGF8a (NP_149355.1) (Gln23-Arg204) is expressed with an initial Met.
Molecular Name	FGF8
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 500mM NaCl, pH8.5
Background	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	21.3 kDa

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