Human THEM2 Protein, His Tag
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Product Number
KMP3225
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Alias
酰基辅酶 A 硫酯酶 13, Human THEM2 Protein, His Tag, THEM2
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 酰基辅酶 A 硫酯酶 13, Human THEM2 Protein, His Tag, THEM2 |
| Catalog Number | KMP3225 |
| Product Description | The Human THEM2 Protein(KMP3225) is produced in E. coli. The target gene encoding the human THEM2 (NP_060943.1) (Met1-Asn140) is expressed with a polyhistidine tag at the N-terminus. |
| Molecular Name | THEM2 |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 50mM Tris, 100mM Arg, pH8.0 |
| Background | The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty acyl-CoAs, but their biological functions remain incompletely understood. Thioesterase superfamily member 2 (Them2; synonym Acot13) is enriched in oxidative tissues, associated with mitochondria, and relatively specific for long chain fatty acyl-CoA substrates. Using Them2(-/-) mice, we have demonstrated key roles for Them2 in regulating hepatic glucose and lipid metabolism. Members of the acyl-CoA thioesterase (Acot) gene family catalyze the hydrolysis of fatty acyl-CoAs, but their biological functions remain unknown. Thioesterase superfamily member 2 (Them2; synonym Acot13) is a broadly expressed mitochondria-associated Acot. Them2 was previously identified as an interacting protein of phosphatidylcholine transfer protein (PC-TP). |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 17.2 kDa |
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