Human IL11 Protein
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Product Number
KMP2992
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Alias
白细胞介素 11, Human IL11 Protein, IL11
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白细胞介素 11, Human IL11 Protein, IL11 |
| Catalog Number | KMP2992 |
| Product Description | The Human IL11 Protein(KMP2992) is produced in E. coli. The target gene encoding the mature form of human IL11 (AAH12506.1) (Pro22-Leu199) is expressed. |
| Molecular Name | IL11 |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation, and could be used as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 19.1 kDa |
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