Human LRP6 Protein, hFc Tag
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Product Number
KMP2961
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Alias
低密度脂蛋白受体相关蛋白6, Human LRP6 Protein, hFc Tag, LRP6
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 低密度脂蛋白受体相关蛋白6, Human LRP6 Protein, hFc Tag, LRP6 |
| Catalog Number | KMP2961 |
| Product Description | The Human LRP6 Protein(KMP2961) is produced in HEK293 Cells. The target gene encoding the Human LRP6 (O75581) (Met1-Pro630) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | LRP6 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Lipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipoprotein (LDL) receptor-related protein-6 (LRP6) is an important co-receptor of Wnt pathway, which plays a predominant role in the development and progression of colorectal cancer. This gene, termed LDL receptor-related protein 6 (LRP6), encodes a transmembrane protein that has 71% identity and is structurally similar to the protein encoded by LRP5, a proposed candidate gene for type 1 diabetes located on human chromosome 11q13. LRP6 maps to human chromosome 12p11-p13. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 95.69 kDa |
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