Human Semaphorin 4D Protein, hFc Tag
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Product Number
KMP2931
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Alias
信号素 4D, Human Semaphorin 4D Protein, hFc Tag, Semaphorin 4D
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 信号素 4D, Human Semaphorin 4D Protein, hFc Tag, Semaphorin 4D |
| Catalog Number | KMP2931 |
| Product Description | The Human Semaphorin 4D Protein(KMP2931) is produced in HEK293 Cells. The target gene encoding the human SEMA4D (AAH54500.1) (Met1-Arg734) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | Semaphorin 4D |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 105.95 kDa |
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