Human Insulin Protein
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Product Number
KMP2835
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Alias
胰岛素, Human Insulin Protein, Insulin
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 胰岛素, Human Insulin Protein, Insulin |
| Catalog Number | KMP2835 |
| Product Description | The Human Insulin Protein(KMP2835) is produced in Yeast. The target gene encoding human insulin B chain (P01308)(Phe25-Lys53) and human insulin A chain (P01308)(Gly90-Asn110) is expressed with a linker AAK. |
| Molecular Name | Insulin |
| Species | Human |
| Host | Yeast |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 7.1 kDa |
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