Human TFRC Protein, hFc Tag
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Product Number
KMP2825
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Alias
转铁蛋白受体1, Human TFRC Protein, hFc Tag, TFRC
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 转铁蛋白受体1, Human TFRC Protein, hFc Tag, TFRC |
| Catalog Number | KMP2825 |
| Product Description | The Human TFRC Protein(KMP2825) is produced in HEK293 Cells. The target gene encoding the human TFRC (CAA25527.1) (Cys89-Phe760) is expressed with the Fc region of human IgG1 at the N-terminus. |
| Molecular Name | TFRC |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 103.6 kDa |
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