Human Syndecan-4 Protein, His Tag
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Product Number
KMP2682
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Alias
联癸烷 4, Human Syndecan-4 Protein, His Tag, Syndecan-4
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 联癸烷 4, Human Syndecan-4 Protein, His Tag, Syndecan-4 |
| Catalog Number | KMP2682 |
| Product Description | The Human Syndecan-4 Protein(KMP2682) is produced in HEK293 Cells. The target gene encoding the human SDC4 (CAA47406.1) (Met1-Glu145) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | Syndecan-4 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with several signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 15.3 kDa |
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