Human NCR3 Protein, hFc Tag
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Product Number
KMP2628
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Alias
天然细胞毒性触发受体 3, Human NCR3 Protein, hFc Tag, NCR3
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 天然细胞毒性触发受体 3, Human NCR3 Protein, hFc Tag, NCR3 |
| Catalog Number | KMP2628 |
| Product Description | The Human NCR3 Protein(KMP2628) is produced in HEK293 Cells. The target gene encoding the human NCR3 (NP_001138938.1) (Met1-Gly135) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | NCR3 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 39.6 kDa |
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