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Human CCL14 Protein, His Tag

Human CCL14 Protein, His Tag

Product Number

KMP2625

Alias

CXC 趋化因子配体 14, Human CCL14 Protein, His Tag, CCL14

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
AliasCXC 趋化因子配体 14, Human CCL14 Protein, His Tag, CCL14
Catalog NumberKMP2625
Product DescriptionThe Human CCL14 Protein(KMP2625) is produced in E. coli. The target gene encoding the mature form of human CCL14 (Q16627-1) (Thr 20-Asn 93) is expressed, with a polyHistide tag at the N-terminus.
Molecular NameCCL14
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH8.0
BackgroundCCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex process involving blastocyst attachment to the endometrial epithelium and subsequent trophoblast invasion of the decidua. We have previously shown that the chemokines CX3CL1 and CCL14 are abundant in endometrial vasculature, epithelial, and decidual cells at this time, and that their receptors, CX3CR1 and CCR1, are present on invading human trophoblasts. CX3CL1 and CCL14 promote trophoblast migration.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight10.2 kDa

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