Human IL-6 Protein
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Product Number
KMP2589
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Alias
白介素6, Human IL-6 Protein, IL-6
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白介素6, Human IL-6 Protein, IL-6 |
| Catalog Number | KMP2589 |
| Product Description | The Human IL-6 Protein(KMP2589) is produced in E. coli. The target gene encoding the mature form of human IL6 (NP_000591.1) (Val30-Met212) is expressed with an initial Met at the N-terminus. |
| Molecular Name | IL-6 |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <0.01 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 20.95 kDa |
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