Human Nectin-2 Protein, His Tag, Avi Tag
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Product Number
KMP2446
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Alias
粘连蛋白细胞粘附分子, Human Nectin-2 Protein, His Tag, Avi Tag, Nectin-2
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 粘连蛋白细胞粘附分子, Human Nectin-2 Protein, His Tag, Avi Tag, Nectin-2 |
| Catalog Number | KMP2446 |
| Product Description | The Human Nectin-2 Protein(KMP2446) is produced in HEK293 Cells. The target gene encoding the human NECTIN2 (NP_002847.1)(Met1-Leu360) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. |
| Molecular Name | Nectin-2 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 38.80 kDa |
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