Human HAVCR2 Protein, His Tag

Name: Human HAVCR2 Protein, His Tag
Brand: KMD Bioscience
SKU: KMP2404

KMP2404

甲型肝炎病毒细胞受体 2, Hepatitis A virus cellular receptor 2, HAVCR2

DATASHEET MSDS

Product Description

Alias	甲型肝炎病毒细胞受体 2, Hepatitis A virus cellular receptor 2, HAVCR2
Catalog Number	KMP2404
Product Description	The Human HAVCR2 Protein(KMP2404) is produced in HEK293 Cells and the target gene encoding Ser22-Arg200 is expressed with a 6His tag at the C-terminus.
Molecular Name	HAVCR2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM PB, 150mM NaCl, pH7.4
Background	T-Cell Membrane Protein 3(TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence(aa 1-21), an extracellular region(aa 22-202) with one Ig-like V-type domain, a transmembrane segment(aa 203-223), and a cytoplasmic domain(aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte(Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
SDS-PAGE
Predicted Molecular Weight	20.7 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	E5RHN3#structure

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