KMP1619
Granulocyte Colony-Stimulating Factor, Granulocyte Colony-Stimulating Factor, G-CSF, human G-CSF Protein, Pluripoietin, Filgrastim, Lenograstim, CSF3, C17orf33, GCSF
| Alias | Granulocyte Colony-Stimulating Factor, Granulocyte Colony-Stimulating Factor, G-CSF, human G-CSF Protein, Pluripoietin, Filgrastim, Lenograstim, CSF3, C17orf33, GCSF |
| Catalog Number | KMP1619 |
| Molecular Name | G-CSF/CSF3 |
| Species | Human |
| Host | E.coli |
| Size | 500ug, 1mg |
| Purity | > 95% as determined by Tris-Bis PAGE, > 95% as determined by HPLC |
| Endotoxin | Less than 0.001 ng/ug (0.01 EU/ug) as determined by LAL test. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.004% Tween 80, 5% Mannitol, pH 4.0. |
| Background | Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17. |
| Application | SDS-PAGE, WB, ELISA |
| Tag | No Tag |
| Predicted N Terminus | Met |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
| Sequence | TPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPEELVLLGHS LGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTL QLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQS FLEVSYRVLRHLAQP |
| Molecular Weight | The protein has a predicted MW of 18.8 kDa. the protein migrates to 16 kDa under reduced (R) condition based on Tris-Bis PAGE result. |
| Uniprot ID | P09919-2 |
| Note | For Research Use Only! |
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