Recombinant Human CDKN1B Protein, His Tag

Name: Recombinant Human CDKN1B Protein, His Tag
Brand: KMD Bioscience
SKU: KMH854

KMH854

KIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B

DATASHEET MSDS

Product Description

Alias	KIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B
Catalog Number	KMH854
Molecular Name	CDKN1B
Species	Human
Host	E. coli
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	Please contact our customer service for more information.
Formulation	PBS
Background	KIP1 (cyclin-dependent kinase inhibitor 1B) is a kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation. Many tumorigenic processes modulate cell-cycle progression by regulating the levels of the cyclin-dependent kinase inhibitor KIP1. KIP1 binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4. The phosphorylation- and ubiquitination-dependent proteolysis of KIP1 is implicated in control of the G1-S transition in the cell cycle. KIP1 is critical for retinoblastoma protein (Rb)-induced cellular proliferative senescence.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	21.78 kDa
Note	仅供科研使用

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