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Recombinant Human Beta-glucuronidase/GLB1 Protein, His Tag

Recombinant Human Beta-glucuronidase/GLB1 Protein, His Tag

Product Number

KMH736

Alias

EBP, ELNR1, MPS4B, galactosidase beta 1

Specifications
  • 50ug
  • 100ug
Product Description
AliasEBP, ELNR1, MPS4B, galactosidase beta 1
Catalog NumberKMH736
Molecular NameGLB1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundGalactosidase is a lysosomal Galactosidase that hydrolyzes the terminal Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex. An alternative splicing at the RNA level of Galactosidase results a catalytically inactive Galactosidase that plays an important role in vascular development. Defects of galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 1 mutations have been identified for Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight71.94 kDa
Note仅供科研使用

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