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Recombinant Human HMGB1 Protein, His Tag

Recombinant Human HMGB1 Protein, His Tag

Product Number

KMH574

Alias

HMG1, HMG3, HMG 1, SBP 1, high mobility group box 1

Specifications
  • 50ug
  • 100ug
Product Description
AliasHMG1, HMG3, HMG 1, SBP 1, high mobility group box 1
Catalog NumberKMH574
Molecular NameHMGB1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationSupplied as solution form in 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA./Lyophilized from 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA.
BackgroundHigh-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 3 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 7 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 3 aa C-terminal region that contains only Asp and Glu.4, 5 Residues 27 - 43 and 178 - 184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight26.97 kDa
Note仅供科研使用

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