Recombinant Human CD358/TNFRSF21 Protein, His Tag

Name: Recombinant Human CD358/TNFRSF21 Protein, His Tag
Brand: KMD Bioscience
SKU: KMH490

KMH490

DR6, CD358, BM 018, TNF receptor superfamily member 21

DATASHEET MSDS

Product Description

Alias	DR6, CD358, BM 018, TNF receptor superfamily member 21
Catalog Number	KMH490
Molecular Name	TNFRSF21
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Death receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region, the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	38.5 kDa
Note	仅供科研使用

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