Recombinant Human CD309/KDR Protein, His Tag

Name: Recombinant Human CD309/KDR Protein, His Tag
Brand: KMD Bioscience
SKU: KMH456

KMH456

FLK1, CD309, VEGFR, VEGFR2, kinase insert domain receptor

DATASHEET MSDS

Product Description

Alias	FLK1, CD309, VEGFR, VEGFR2, kinase insert domain receptor
Catalog Number	KMH456
Molecular Name	KDR
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	KDR (or kinase insert domain receptor) is a growth factor receptor tyrosine kinase that was originally isolated from human endothelial cells where it plays a pivotal role in endothelial cell proliferation and differentiation. KDR and its mouse homolog Flk1 bind VEGF with high affinity and are implicated in the development of new blood vessels (angiogenesis). The expression levels of VEGF and KDR are highly correlated during the normal development of the ocular vasculature in humans (1). Induction of angiogenesis is a critical step in tumor progression, and inhibitors of KDR have been demonstrated both to induce tumor regression and reduce metastatic potential in preclinical models.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	35.97 kDa
Note	仅供科研使用

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